MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis I in Burkholderia phytofirmans PsJN

Add experiment(s):


a malonyl-[acp] + S-adenosyl-L-methionine→a malonyl-[acp] methyl ester + S-adenosyl-L-homocysteine (EC 2.1.1.197)
No genes
Beta-ketoacyl-acyl-carrier-protein synthase II:
a malonyl-[acp] + a malonyl-[acp] methyl ester + H+→a 3-oxoglutaryl-[acp] methyl ester + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
BPHYT_RS14415
BPHYT_RS15125
BPHYT_RS15130
BPHYT_RS15145
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxoglutaryl-[acp] methyl ester + NADPH + H+→a (3R)-3-hydroxyglutaryl-[acp] methyl ester + NADP+ (EC 1.1.1.100)
BPHYT_RS01050
BPHYT_RS04770
BPHYT_RS05365
BPHYT_RS05385
BPHYT_RS06420
BPHYT_RS07065
BPHYT_RS08285
BPHYT_RS08365
BPHYT_RS08890
BPHYT_RS10170
BPHYT_RS10200
BPHYT_RS10595
BPHYT_RS10630
BPHYT_RS10735
BPHYT_RS11845
BPHYT_RS13055
BPHYT_RS14425
BPHYT_RS15135
BPHYT_RS15890
BPHYT_RS16040
BPHYT_RS16940
BPHYT_RS20510
BPHYT_RS20625
BPHYT_RS20775
BPHYT_RS21600
BPHYT_RS22135
BPHYT_RS25030
BPHYT_RS25415
BPHYT_RS25655
BPHYT_RS26470
BPHYT_RS28250
BPHYT_RS30440
BPHYT_RS30465
BPHYT_RS30795
BPHYT_RS31385
BPHYT_RS31405
BPHYT_RS31610
BPHYT_RS31900
BPHYT_RS33140
BPHYT_RS33705
BPHYT_RS34945
BPHYT_RS34965
BPHYT_RS35505
BPHYT_RS35675
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyglutaryl-[acp] methyl ester→a (2E)-enoylglutaryl-[acp] methyl ester + H2O (EC 4.2.1.59)
BPHYT_RS12085
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-enoylglutaryl-[acp] methyl ester + NADH + H+→a glutaryl-[acp] methyl ester + NAD+ (EC 1.3.1.9)
BPHYT_RS01880
BPHYT_RS12390
BPHYT_RS20615
BPHYT_RS30015
BPHYT_RS33380
Beta-ketoacyl-acyl-carrier-protein synthase II:
a glutaryl-[acp] methyl ester + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] methyl ester + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
BPHYT_RS14415
BPHYT_RS15125
BPHYT_RS15130
BPHYT_RS15145
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxopimeloyl-[acp] methyl ester + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] methyl ester + NADP+ (EC 1.1.1.100)
BPHYT_RS01050
BPHYT_RS04770
BPHYT_RS05365
BPHYT_RS05385
BPHYT_RS06420
BPHYT_RS07065
BPHYT_RS08285
BPHYT_RS08365
BPHYT_RS08890
BPHYT_RS10170
BPHYT_RS10200
BPHYT_RS10595
BPHYT_RS10630
BPHYT_RS10735
BPHYT_RS11845
BPHYT_RS13055
BPHYT_RS14425
BPHYT_RS15135
BPHYT_RS15890
BPHYT_RS16040
BPHYT_RS16940
BPHYT_RS20510
BPHYT_RS20625
BPHYT_RS20775
BPHYT_RS21600
BPHYT_RS22135
BPHYT_RS25030
BPHYT_RS25415
BPHYT_RS25655
BPHYT_RS26470
BPHYT_RS28250
BPHYT_RS30440
BPHYT_RS30465
BPHYT_RS30795
BPHYT_RS31385
BPHYT_RS31405
BPHYT_RS31610
BPHYT_RS31900
BPHYT_RS33140
BPHYT_RS33705
BPHYT_RS34945
BPHYT_RS34965
BPHYT_RS35505
BPHYT_RS35675
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxypimeloyl-[acp] methyl ester→a (2E)-enoylpimeloyl-[acp] methyl ester + H2O (EC 4.2.1.59)
BPHYT_RS12085
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-enoylpimeloyl-[acp] methyl ester + NADH + H+→a pimeloyl-[acp] methyl ester + NAD+ (EC 1.3.1.9)
BPHYT_RS01880
BPHYT_RS12390
BPHYT_RS20615
BPHYT_RS30015
BPHYT_RS33380
a pimeloyl-[acp] methyl ester + H2O→a pimeloyl-[acp] + methanol + H+ (EC 3.1.1.85)
No genes
8-amino-7-oxononanoate synthase:
a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)
BPHYT_RS02160

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information