MetaCyc Pathway: noradrenaline and adrenaline degradation in Burkholderia phytofirmans PsJN

Add experiment(s):


Catechol O-methyltransferase:
(R)-noradrenaline + S-adenosyl-L-methionine→L-normetanephrine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Monoamine oxidase:
(R)-noradrenaline + dioxygen + H2O→3,4-dihydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
No genes
Phenylethanolamine N-methyltransferase:
(R)-noradrenaline + S-adenosyl-L-methionine→(R)-adrenaline + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.28)
No genes
Monoamine oxidase:
(R)-adrenaline + dioxygen + H2O→3,4-dihydroxyphenylglycolaldehyde + hydrogen peroxide + methylamine (EC 1.4.3.4)
No genes
Catechol O-methyltransferase:
(R)-adrenaline + S-adenosyl-L-methionine→metanephrine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Monoamine oxidase:
L-normetanephrine + dioxygen + H2O→3-methoxy-4-hydroxyphenylglycolaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
No genes
Alcohol dehydrogenase (in reverse):
3,4-dihydroxyphenylglycolaldehyde + NADH + H+→(R)-3,4-dihydroxyphenylglycol + NAD+ (EC 1.1.1.1)
BPHYT_RS00510
BPHYT_RS16150
BPHYT_RS20205
BPHYT_RS24470
BPHYT_RS25430
BPHYT_RS27390
BPHYT_RS28135
BPHYT_RS30075
BPHYT_RS31305
BPHYT_RS31860
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylglycolaldehyde + NAD+ + H2O→3,4-dihydroxymandelate + NADH + 2 H+ (EC 1.2.1.3)
BPHYT_RS00120
BPHYT_RS00395
BPHYT_RS05370
BPHYT_RS07490
BPHYT_RS09900
BPHYT_RS17340
BPHYT_RS18745
BPHYT_RS19710
BPHYT_RS20795
BPHYT_RS25705
BPHYT_RS25810
BPHYT_RS27405
BPHYT_RS28770
BPHYT_RS29875
BPHYT_RS30510
BPHYT_RS32650
BPHYT_RS34980
BPHYT_RS35600
Monoamine oxidase:
metanephrine + dioxygen + H2O→3-methoxy-4-hydroxyphenylglycolaldehyde + hydrogen peroxide + methylamine (EC 1.4.3.4)
No genes
Catechol O-methyltransferase:
(R)-3,4-dihydroxyphenylglycol + S-adenosyl-L-methionine→3-methoxy-4-hydroxyphenylglycol + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Catechol O-methyltransferase:
3,4-dihydroxymandelate + S-adenosyl-L-methionine→vanillylmandelate + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Alcohol dehydrogenase:
3-methoxy-4-hydroxyphenylglycol + NAD+→3-methoxy-4-hydroxyphenylglycolaldehyde + NADH + H+ (EC 1.1.1.1)
BPHYT_RS00510
BPHYT_RS16150
BPHYT_RS20205
BPHYT_RS24470
BPHYT_RS25430
BPHYT_RS27390
BPHYT_RS28135
BPHYT_RS30075
BPHYT_RS31305
BPHYT_RS31860
Aldehyde dehydrogenase (NAD(+)):
3-methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O→vanillylmandelate + NADH + 2 H+ (EC 1.2.1.3)
BPHYT_RS00120
BPHYT_RS00395
BPHYT_RS05370
BPHYT_RS07490
BPHYT_RS09900
BPHYT_RS17340
BPHYT_RS18745
BPHYT_RS19710
BPHYT_RS20795
BPHYT_RS25705
BPHYT_RS25810
BPHYT_RS27405
BPHYT_RS28770
BPHYT_RS29875
BPHYT_RS30510
BPHYT_RS32650
BPHYT_RS34980
BPHYT_RS35600

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information