MetaCyc Pathway: 4,5-dichlorocatechol degradation in Burkholderia phytofirmans PsJN

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4,5-dichlorobenzene-1,2-diol + dioxygen→2,3-dichloro-cis,cis-muconate + 2 H+ (EC 1.13.11.M6)
No genes
Chloromuconate cycloisomerase (in reverse):
2,3-dichloro-cis,cis-muconate + H+→2-chloro-2-(2-chloro-5-oxofuran-2-yl)acetate (EC 5.5.1.7)
No genes
2-chloro-2-(2-chloro-5-oxofuran-2-yl)acetate→5-chloro-trans-dienelactone + chloride + H+ (spontaneous)
No genes
Carboxymethylenebutenolidase:
5-chloro-trans-dienelactone + H2O→5-chloromaleylacetate + H+ (EC 3.1.1.45)
BPHYT_RS01875
BPHYT_RS20505
BPHYT_RS33600
BPHYT_RS35440
Maleylacetate reductase (in reverse):
5-chloromaleylacetate + NAD(P)H + H+→5-chloro-3-oxoadipate + NAD(P)+ (EC 1.3.1.32)
No genes
5-chloro-3-oxoadipate→2-maleylacetate + chloride + H+ (spontaneous)
No genes
Maleylacetate reductase (in reverse):
2-maleylacetate + NAD(P)H + H+→3-oxoadipate + NAD(P)+ (EC 1.3.1.32)
BPHYT_RS25705

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information