MetaCyc Pathway: indole-3-acetate biosynthesis II in Burkholderia phytofirmans PsJN

Add experiment(s):


L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
BPHYT_RS34205
L-tryptophan + dioxygen + a reduced [NADPH-hemoprotein reductase]→N2-hydroxy-L-tryptophan + an oxidized [NADPH-hemoprotein reductase] + H+ + H2O (EC 1.14.14.156)
No genes
Aspartate transaminase:
L-tryptophan + 2-oxoglutarate→(indol-3-yl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27)
BPHYT_RS00155
BPHYT_RS04100
BPHYT_RS05430
BPHYT_RS05975
BPHYT_RS06770
BPHYT_RS08040
BPHYT_RS08950
BPHYT_RS09580
BPHYT_RS10265
BPHYT_RS10440
BPHYT_RS13065
BPHYT_RS13450
BPHYT_RS15405
BPHYT_RS15820
BPHYT_RS21060
BPHYT_RS21560
BPHYT_RS21610
BPHYT_RS21730
BPHYT_RS22065
BPHYT_RS22425
BPHYT_RS26535
BPHYT_RS27000
BPHYT_RS28370
BPHYT_RS28685
BPHYT_RS28695
BPHYT_RS30590
BPHYT_RS30680
BPHYT_RS35285
N2-hydroxy-L-tryptophan + dioxygen + a reduced [NADPH-hemoprotein reductase]→N2,N2-dihydroxy-L-tryptophan + an oxidized [NADPH-hemoprotein reductase] + H2O (EC 1.14.14.156)
No genes
tryptamine + NADPH + dioxygen→N-hydroxyl-tryptamine + NADP+ + H2O
No genes
(indol-3-yl)pyruvate + NADPH + dioxygen + H+→(indol-3-yl)acetate + CO2 + NADP+ + H2O (EC 1.14.13.168)
No genes
N-hydroxyl-tryptamine + an oxidized electron carrier→(E)-(indol-3-yl)acetaldehyde oxime + a reduced two electron carrier
No genes
N2,N2-dihydroxy-L-tryptophan + H+→(E)-(indol-3-yl)acetaldehyde oxime + CO2 + H2O (spontaneous) (EC 1.14.14.156)
No genes
(E)-(indol-3-yl)acetaldehyde oxime→(indol-3-yl)acetonitrile + H2O (EC 4.8.1.3)
No genes
Nitrilase:
(indol-3-yl)acetonitrile + 2 H2O→(indol-3-yl)acetate + ammonium (EC 3.5.5.1)
BPHYT_RS03545
BPHYT_RS20670
Nitrile hydratase (in reverse):
(indol-3-yl)acetonitrile + H2O→(indol-3-yl)acetamide (EC 4.2.1.84)
BPHYT_RS25305
BPHYT_RS25310
BPHYT_RS35545
BPHYT_RS35550
Amidase:
(indol-3-yl)acetamide + H2O→(indol-3-yl)acetate + ammonium (EC 3.5.1.4)
BPHYT_RS00250
BPHYT_RS01870
BPHYT_RS10730
BPHYT_RS10765
BPHYT_RS26095
BPHYT_RS28340
BPHYT_RS28545
BPHYT_RS29965
BPHYT_RS31780

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information