MetaCyc Pathway: glutathione-mediated detoxification I in Burkholderia phytofirmans PsJN

Add experiment(s):


Glutathione transferase:
RX + glutathione→a glutathione-S-conjugate + HX (EC 2.5.1.18)
BPHYT_RS01295
BPHYT_RS02805
BPHYT_RS03255
BPHYT_RS05050
BPHYT_RS05420
BPHYT_RS05630
BPHYT_RS06735
BPHYT_RS06765
BPHYT_RS07080
BPHYT_RS07530
BPHYT_RS07725
BPHYT_RS09970
BPHYT_RS11320
BPHYT_RS16570
BPHYT_RS18410
BPHYT_RS18600
BPHYT_RS25260
BPHYT_RS25515
BPHYT_RS25625
BPHYT_RS25630
BPHYT_RS26415
BPHYT_RS26475
BPHYT_RS26495
BPHYT_RS26500
BPHYT_RS30555
BPHYT_RS32970
BPHYT_RS34135
BPHYT_RS35435
a glutathione-S-conjugate[in] + ATP[in] + H2O[in]→a glutathione-S-conjugate[out] + ADP[in] + H+[in] + phosphate[in] (EC 7.6.2.3)
No genes
a glutathione-S-conjugate + H2O→an (L-cysteinylglycine)-S-conjugate + L-glutamate (EC 3.4.19.13)
No genes
an (L-cysteinylglycine)-S-conjugate + H2O→an L-cysteine-S-conjugate + glycine (EC 3.4.13.23)
No genes
Cysteine-S-conjugate N-acetyltransferase:
an L-cysteine-S-conjugate + acetyl-CoA→a mercapturate + coenzyme A + H+ (EC 2.3.1.80)
No genes
Cysteine-S-conjugate beta-lyase:
an L-cysteine-S-conjugate→2-aminoprop-2-enoate + a thiol (EC 4.4.1.13)
No genes
Tryptophanase:
2-aminoprop-2-enoate→2-iminopropanoate (spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
BPHYT_RS03115
BPHYT_RS19340
BPHYT_RS25100
2-iminopropanoate + H2O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
BPHYT_RS03115
BPHYT_RS19340
BPHYT_RS25100
BPHYT_RS29300

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information