MetaCyc Pathway: phosphopantothenate biosynthesis I in Burkholderia phytofirmans PsJN

Add experiment(s):


3-methyl-2-oxobutanoate hydroxymethyltransferase:
3-methyl-2-oxobutanoate + a 5,10-methylenetetrahydrofolate + H2O→2-dehydropantoate + a tetrahydrofolate (EC 2.1.2.11)
BPHYT_RS03605
2-dehydropantoate 2-reductase (in reverse):
2-dehydropantoate + NADPH + H+→(R)-pantoate + NADP+ (EC 1.1.1.169)
BPHYT_RS06555
BPHYT_RS21975
BPHYT_RS25635
BPHYT_RS26745
BPHYT_RS27355
BPHYT_RS29870
Pantoate--beta-alanine ligase:
(R)-pantoate + β-alanine + ATP→(R)-pantothenate + AMP + diphosphate + H+ (EC 6.3.2.1)
BPHYT_RS04925
Pantothenate kinase:
(R)-pantothenate + ATP→(R)-4'-phosphopantothenate + ADP + H+ (EC 2.7.1.33)
BPHYT_RS02370

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information