MetaCyc Pathway: superpathway of glycolysis and the Entner-Doudoroff pathway in Burkholderia phytofirmans PsJN

Add experiment(s):


Glucose-6-phosphate dehydrogenase:
D-glucopyranose 6-phosphate + NADP+→6-phospho D-glucono-1,5-lactone + NADPH + H+ (EC 1.1.1.49)
BPHYT_RS05020
BPHYT_RS24370
BPHYT_RS35135
D-glucopyranose[out] + an [HPr protein]-Nπ-phospho-L-histidine[in]→D-glucopyranose 6-phosphate[in] + an [HPr]-L-histidine[in] (EC 2.7.1.199)
No genes
6-phosphogluconolactonase:
6-phospho D-glucono-1,5-lactone + H2O→D-gluconate 6-phosphate + H+ (EC 3.1.1.31)
BPHYT_RS05015
BPHYT_RS06110
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
BPHYT_RS09500
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
No genes
Phosphogluconate dehydratase:
D-gluconate 6-phosphate→2-dehydro-3-deoxy-D-gluconate 6-phosphate + H2O (EC 4.2.1.12)
BPHYT_RS16735
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
BPHYT_RS10545
BPHYT_RS16260
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
BPHYT_RS15225
2-dehydro-3-deoxy-phosphogluconate aldolase:
2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate (EC 4.1.2.14; 4.1.2.55)
BPHYT_RS16730
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
BPHYT_RS16835
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
BPHYT_RS06610
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
BPHYT_RS16270
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
BPHYT_RS02590
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
BPHYT_RS02590
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
BPHYT_RS12675
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
BPHYT_RS16265
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
BPHYT_RS11465
BPHYT_RS12055

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information