MetaCyc Pathway: mixed acid fermentation in Burkholderia phytofirmans PsJN

Add experiment(s):


Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
BPHYT_RS05225
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
BPHYT_RS16265
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
BPHYT_RS03835
BPHYT_RS10205
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
BPHYT_RS27110
BPHYT_RS28460
BPHYT_RS33955
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
No genes
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
BPHYT_RS07245
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
BPHYT_RS15810
BPHYT_RS19980
BPHYT_RS20940
BPHYT_RS27440
BPHYT_RS33920
formate + H+→CO2 + H2
No genes
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
BPHYT_RS06985
BPHYT_RS14615
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
BPHYT_RS21700
BPHYT_RS27695
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
BPHYT_RS06125
BPHYT_RS26200
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
BPHYT_RS10160
BPHYT_RS30145
BPHYT_RS33980
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
BPHYT_RS00510
BPHYT_RS16150
BPHYT_RS20205
BPHYT_RS24470
BPHYT_RS25430
BPHYT_RS27390
BPHYT_RS28135
BPHYT_RS30075
BPHYT_RS31305
BPHYT_RS31860
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
No genes
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
BPHYT_RS10160
BPHYT_RS30145
BPHYT_RS33980
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→CO2 + 2-oxoglutarate + NADPH (EC 1.1.1.42)
BPHYT_RS15730
BPHYT_RS20300

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information