MetaCyc Pathway: lipoprotein posttranslational modification (Gram-negative bacteria) in Shewanella sp. ANA-3

Add experiment(s):


a [prolipoprotein]-L-cysteine[in]→a [prolipoprotein]-L-cysteine[membrane]
No genes
a [prolipoprotein]-L-cysteine + a phosphatidylglycerol→a [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine + H+ + sn-glycerol 1-phosphate (EC 2.5.1.145)
No genes
Signal peptidase II:
a [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine + H2O→an (S-diacyl-sn-glyceryl)-L-cysteinyl-[apolipoprotein] + a lipoprotein signal peptide (EC 3.4.23.36)
Shewana3_4152
Shewana3_4320
Shewana3_3135 (lspA)
an (S-diacyl-sn-glyceryl)-L-cysteinyl-[apolipoprotein] + a phosphoglyceride→an N-acyl-(S-diacyl-sn-glyceryl)-L-cysteinyl-[lipoprotein] + a 1-lysophospholipid + H+ (EC 2.3.1.269)
No genes
a lipoprotein signal peptide + n H2O→n+1 a peptide
Shewana3_2808
an N-acyl-(S-diacyl-sn-glyceryl)-L-cysteinyl-[lipoprotein][membrane] + ATP[in] + a LolA lipoprotein chaperone[out] + H2O[in]→a LolA-lipoprotein complex[out] + ADP[in] + H+[in] + phosphate[in]
Shewana3_1538
Shewana3_2285
Shewana3_2286
Shewana3_3260
Shewana3_3971
a LolA-lipoprotein complex[in]→an N-acyl-(S-diacyl-sn-glyceryl)-L-cysteinyl-[lipoprotein][membrane] + a LolA lipoprotein chaperone[in]
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information