MetaCyc Pathway: glycine degradation in Pseudomonas fluorescens FW300-N2E2

Reactions and Genes	Cytidine (N)
glycine + NAD+ + a tetrahydrofolate→ammonium + a 5,10-methylenetetrahydrofolate + CO2 + NADH (EC 1.4.1.27)
Pf6N2E2_4251	+0.0
Pf6N2E2_4485	+0.3
Pf6N2E2_5857	N.D.
Glycine hydroxymethyltransferase (in reverse): glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate (EC 2.1.2.1)
Pf6N2E2_4717	+0.1
Pf6N2E2_5082	N.D.
Pf6N2E2_5083	-1.0
Pf6N2E2_5295	-0.2
L-serine ammonia-lyase: L-serine→ammonium + pyruvate (EC 4.3.1.17)
Pf6N2E2_4685	+0.1
Pf6N2E2_5557	+0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information