MetaCyc Pathway: L-tyrosine degradation IV (to 4-methylphenol) in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes L-Phenylalanine (N)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Pf6N2E2_1496 -0.1
Pf6N2E2_2127 -0.0
Pf6N2E2_2446 +0.0
Pf6N2E2_2519 +0.2
Pf6N2E2_2632 -3.8
Pf6N2E2_3173 +0.1
Pf6N2E2_3251 -5.3
Pf6N2E2_4288 +0.1
Pf6N2E2_4386 +0.1
Pf6N2E2_462 +0.1
Pf6N2E2_50 -0.5
Pf6N2E2_5300 -1.3
Pf6N2E2_5813 -0.2
Pf6N2E2_5890 +0.0
Pf6N2E2_5891 N.D.
Pf6N2E2_5895 -0.1
Pf6N2E2_5989 +0.3
Pf6N2E2_637 -0.2
Pf6N2E2_684 +0.1
4-hydroxyphenylpyruvate oxidase:
2 3-(4-hydroxyphenyl)pyruvate + dioxygen→2 (4-hydroxyphenyl)acetate + 2 CO2
(EC 1.2.3.13)
No genes
4-hydroxyphenylacetate decarboxylase:
(4-hydroxyphenyl)acetate + H+→4-methylphenol + CO2
(EC 4.1.1.83)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information