MetaCyc Pathway: L-phenylalanine degradation VI (reductive Stickland reaction) in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Cadmium chloride hemipentahydrate 0.000015625 M
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Aspartate transaminase:
L-phenylalanine + 2-oxoglutarate→3-phenyl-2-oxopropanoate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
Pf6N2E2_1496 -0.1
Pf6N2E2_2127 +2.4
Pf6N2E2_2446 +0.0
Pf6N2E2_2519 +0.1
Pf6N2E2_2632 -0.3
Pf6N2E2_3173 +0.2
Pf6N2E2_3251 +0.7
Pf6N2E2_4288 +0.1
Pf6N2E2_4386 -0.1
Pf6N2E2_462 +0.0
Pf6N2E2_50 -0.2
Pf6N2E2_5300 +1.6
Pf6N2E2_5813 +0.0
Pf6N2E2_5890 -0.1
Pf6N2E2_5891 N.D.
Pf6N2E2_5895 +0.1
Pf6N2E2_5989 +2.2
Pf6N2E2_637 -0.0
Pf6N2E2_684 -0.0
Indolelactate dehydrogenase (in reverse):
3-phenyl-2-oxopropanoate + NADH + H+→(R)-3-(phenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(phenyl)lactate + (E)-cinnamoyl-CoA→(R)-3-(phenyl)lactoyl-CoA + trans-cinnamate (EC 2.8.3.17)
No genes
trans-cinnamate + a reduced electron-transfer flavoprotein→3-phenylpropanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(phenyl)lactoyl-CoA→(E)-cinnamoyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information