MetaCyc Pathway: coenzyme M biosynthesis II in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Cadmium chloride hemipentahydrate 0.000015625 M
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O-phospho-L-serine + H+ + sulfite→L-cysteate + phosphate (EC 2.5.1.76)
No genes
Aspartate transaminase:
L-cysteate + 2-oxoglutarate→3-sulfopyruvate + L-glutamate
(EC 2.6.1.1)
Pf6N2E2_1496 -0.1
Pf6N2E2_2127 +2.4
Pf6N2E2_2446 +0.0
Pf6N2E2_2632 -0.3
Pf6N2E2_3173 +0.2
Pf6N2E2_4288 +0.1
Pf6N2E2_4386 -0.1
Pf6N2E2_462 +0.0
Pf6N2E2_5300 +1.6
Pf6N2E2_5813 +0.0
Pf6N2E2_5890 -0.1
Pf6N2E2_5891 N.D.
Pf6N2E2_5895 +0.1
Pf6N2E2_5989 +2.2
Pf6N2E2_637 -0.0
Pf6N2E2_684 -0.0
Sulfopyruvate decarboxylase:
3-sulfopyruvate + H+→sulfoacetaldehyde + CO2
(EC 4.1.1.79)
No genes
sulfoacetaldehyde + L-cysteine→2-(sulfomethyl)thiazolidine-4-carboxylate + H+ + H2O
No genes
2-(sulfomethyl)thiazolidine-4-carboxylate + a reduced two electron carrier + H+→sulfoethylcysteine + an oxidized electron carrier
No genes
sulfoethylcysteine + H2O→coenzyme M + ammonium + pyruvate
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information