MetaCyc Pathway: ureide biosynthesis in Enterobacter sp. TBS_079

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Reactions and Genes Adenosine (C)
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IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+
(EC 1.1.1.205)
MPMX20_03382 -3.4
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate
(EC 3.1.3.5)
MPMX20_00273 +0.3
MPMX20_00672 +0.0
MPMX20_01081 +0.2
MPMX20_03221 -0.1
MPMX20_03630 -0.3
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate
(EC 2.4.2.1)
MPMX20_00683 -4.2
MPMX20_00981 -0.4
MPMX20_03300 +0.2
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+
(EC 1.17.1.4)
No genes
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide
(EC 1.7.3.3)
MPMX20_01656 -0.2
MPMX20_01662 +0.2
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+
(EC 3.5.2.17)
MPMX20_00072 -0.1
MPMX20_01657 +0.1
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
MPMX20_01656 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information