MetaCyc Pathway: NAD salvage pathway I (PNC VI cycle) in Sinorhizobium meliloti 1021

Reactions and Genes	Protocatechuic Acid (C)
NAD(+) synthase (glutamine-hydrolyzing): nicotinate adenine dinucleotide + ATP + L-glutamine + H2O→NAD+ + AMP + L-glutamate + diphosphate + H+ (EC 6.3.5.1)
SMc00161	N.D.
NAD(+) diphosphatase: NAD+ + H2O→β-nicotinamide D-ribonucleotide + AMP + 2 H+ (EC 3.6.1.22)
SMc01878	N.D.
SMc02903	+1.1
NMN nucleosidase: β-nicotinamide D-ribonucleotide + H2O→nicotinamide + D-ribofuranose 5-phosphate + H+ (EC 3.2.2.14; 3.2.2.6)
No genes
Nicotinamidase: nicotinamide + H2O→nicotinate + ammonium (EC 3.5.1.19)
SMc02275	+0.1
nicotinate + ATP + 5-phospho-α-D-ribose 1-diphosphate + H2O→β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate (EC 6.3.4.21)
SMc02276	-0.8
Nicotinate-nucleotide adenylyltransferase: β-nicotinate D-ribonucleotide + ATP + H+→nicotinate adenine dinucleotide + diphosphate (EC 2.7.7.18)
SMc03778	N.D.
NAD(+) synthase: nicotinate adenine dinucleotide + ammonium + ATP→NAD+ + AMP + diphosphate + H+ (EC 6.3.1.5)
SM_b20649	-0.1
SMc00161	N.D.

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information