MetaCyc Pathway: fatty acid β-oxidation I (generic) in Sinorhizobium meliloti 1021

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Reactions and Genes Protocatechuic Acid (C)
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a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Dodecenoyl-CoA isomerase:
a (3Z)-3-enoyl-CoA→a (2E)-2-enoyl-CoA
(EC 5.3.3.8)
SM_b21632 +0.1
3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 5.1.2.3)
SM_b21632 +0.1
SMc02227 -0.7
a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+→a (2E)-2-enoyl-CoA + a reduced electron-transfer flavoprotein
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
SM_b20752 +0.1
SM_b21632 +0.1
SM_b21633 +0.2
SMa1408 -0.0
SMc00976 -0.5
SMc01153 +0.1
SMc01638 +0.0
SMc01641 +0.8
SMc01669 +0.1
SMc01806 +0.2
SMc02227 -0.7
SMc04398 N.D.
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
SM_b21632 +0.1
SMc01638 +0.0
SMc02227 -0.7
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
SM_b20589 -5.0
SMa1450 +0.0
SMc00262 -0.1
SMc00966 -0.2
SMc02228 -0.9
SMc03879 -0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information