MetaCyc Pathway: superpathway of anaerobic sucrose degradation in Sinorhizobium meliloti 1021

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Reactions and Genes pipercolic (C)
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Sucrose synthase (in reverse):
sucrose + H+ + UDP→β-D-fructofuranose + UDP-α-D-glucose (EC 2.4.1.13)
No genes
Fructokinase:
β-D-fructofuranose + ATP→β-D-fructofuranose 6-phosphate + ADP + H+ (EC 2.7.1.4)
SM_b21374 -1.3
SMc02164 -1.4
SMc02846 +0.0
SMc03109 +0.0
UTP-monosaccharide-1-phosphate uridylyltransferase (in reverse):
UDP-α-D-glucose + diphosphate→α-D-glucopyranose 1-phosphate + H+ + UTP (EC 2.7.7.64; 2.7.7.9)
SM_b20960 +0.1
SMc04023 +0.0
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
SM_b21373 +0.2
Phosphoglucomutase:
α-D-glucopyranose 1-phosphate→D-glucopyranose 6-phosphate (EC 5.4.2.2)
SM_b21081 -0.1
SMc00637 N.D.
SMc03925 N.D.
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
SM_b20199 -2.8
SM_b20498 +0.1
SM_b21192 +0.3
SMc03983 +0.2
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
SM_b20202 -0.5
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
SM_b20857 +0.1
SMc02042 -0.1
SMc02163 N.D.
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
SMc01023 +0.3
SMc01614 +0.1
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
SMc03979 -5.1
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
SMc03981 -7.0
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
SMc02838 -8.5
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
No genes
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
SMc01028 -6.4
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
SMc04005 +0.2
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
No genes
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
No genes
Pyruvate decarboxylase:
pyruvate + H+→acetaldehyde + CO2 (EC 4.1.1.1)
No genes
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
SM_b20147 +0.0
SM_b20170 N.D.
SMa0263 +0.2
SMa1296 -0.5
SMa2113 -0.0
SMc00105 +0.1
SMc00680 -0.3
SMc01270 N.D.
SMc01582 -0.0
SMc01816 +0.0
SMc03929 +0.0
SMc04270 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information