MetaCyc Pathway: polyhydroxybutanoate biosynthesis in Sinorhizobium meliloti 1021

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Reactions and Genes 5-Aminovaleric (C)
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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A
(EC 2.3.1.16; 2.3.1.9)
SM_b20589 +0.1
SMa1450 +0.1
SMc00262 -0.5
SMc00966 +0.2
SMc02228 -2.2
SMc03879 -5.4
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+
(EC 1.1.1.36)
SMc03878 +0.8
(3R)-3-hydroxybutanoyl-CoA + poly-[(R)-3-hydroxybutanoate]→poly-[(R)-3-hydroxybutanoate] + coenzyme A (EC 2.3.1.304)
SMc01652 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information