MetaCyc Pathway: mannitol cycle in Sinorhizobium meliloti 1021

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Reactions and Genes D-Mannose (C)
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Fructokinase:
β-D-fructofuranose + ATP→β-D-fructofuranose 6-phosphate + ADP + H+ (EC 2.7.1.4)
SM_b21374 -0.3
SMc02164 -0.6
SMc02846 +0.0
SMc03109 -5.3
Mannitol-1-phosphate 5-dehydrogenase (in reverse):
β-D-fructofuranose 6-phosphate + NADH + H+→D-mannitol 1-phosphate + NAD+ (EC 1.1.1.17)
No genes
Mannitol-1-phosphatase:
D-mannitol 1-phosphate + H2O→D-mannitol + phosphate (EC 3.1.3.22)
No genes
Mannitol 2-dehydrogenase:
D-mannitol + NAD+→keto-D-fructose + NADH + H+ (EC 1.1.1.67)
SMc01501 -0.1
SMc02034 -0.1
keto-D-fructose→β-D-fructofuranose (spontaneous)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information