MetaCyc Pathway: stearate biosynthesis IV in Sinorhizobium meliloti 1021

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Reactions and Genes Myristic (C)
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Beta-ketoacyl-acyl-carrier-protein synthase I:
a palmitoyl-[acp] + a malonyl-[acp] + H+→a 3-oxooctadecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.41)
SMc00327 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxooctadecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyoctadecanoyl-[acp] + NADP+ (EC 1.1.1.100)
SM_b20073 +0.2
SM_b20210 -0.2
SM_b20493 -0.1
SM_b20511 -0.1
SM_b20871 +0.1
SM_b21383 -0.1
SM_b21474 +0.0
SMa0059 +0.1
SMa0074 -0.0
SMa0187 +0.0
SMa0329 -0.2
SMa0335 +0.2
SMa0389 +0.1
SMa0854 -0.0
SMa0959 -0.3
SMa1367 +0.1
SMa1398 +0.0
SMa1629 +0.1
SMa1967 +0.1
SMa2019 N.D.
SMa2165 -0.1
SMc00136 +0.2
SMc00260 -0.3
SMc00264 -0.0
SMc00268 -0.1
SMc00372 -0.0
SMc00572 N.D.
SMc00778 -0.2
SMc00880 -0.1
SMc01157 N.D.
SMc01571 +0.0
SMc01991 -0.5
SMc02037 -0.5
SMc02041 -0.6
SMc02522 -0.0
SMc04391 -0.6
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyoctadecanoyl-[acp]→a (2E)-octadec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
SMc00328 N.D.
SMc02092 N.D.
SMc04277 N.D.
a (2E)-octadec-2-enoyl-[acp] + NADPH + H+→a stearoyl-[acp] + NADP+ (EC 1.3.1.104)
No genes
Oleoyl-[acyl-carrier-protein] hydrolase:
a stearoyl-[acp] + H2O→stearate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
Long-chain-fatty-acid--CoA ligase:
stearate + ATP + coenzyme A→stearoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
SMc02162 -5.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information