MetaCyc Pathway: L-leucine degradation III in Klebsiella michiganensis M5al

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Reactions and Genes RCH2_defined_Glucose_noNitrogen in Eppendorf tube with 0.1 mM glass beads
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Branched-chain-amino-acid transaminase:
L-leucine + 2-oxoglutarate→4-methyl-2-oxopentanoate + L-glutamate (EC 2.6.1.42; 2.6.1.6)
BWI76_RS00970 -0.8
BWI76_RS01925 -0.0
BWI76_RS10365 -0.1
BWI76_RS24235 +0.4
Branched-chain-2-oxoacid decarboxylase:
4-methyl-2-oxopentanoate + H+→3-methylbutanal + CO2 (EC 4.1.1.72)
No genes
Alcohol dehydrogenase (in reverse):
3-methylbutanal + NADH + H+→3-methylbutanol + NAD+ (EC 1.1.1.1)
BWI76_RS00645 -0.1
BWI76_RS02835 +0.2
BWI76_RS03140 -0.1
BWI76_RS03320 -0.1
BWI76_RS12395 +0.1
BWI76_RS13800 -0.1
BWI76_RS15240 +0.2
BWI76_RS17250 -1.5
BWI76_RS25510 +0.4
BWI76_RS27960 +0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information