MetaCyc Pathway: FeMo cofactor biosynthesis in Klebsiella michiganensis M5al

Reactions and Genes	RCH2_defined_Glucose_noNitrogen in Eppendorf tube
Homocitrate synthase: 2-oxoglutarate + acetyl-CoA + H2O→(2R)-homocitrate + coenzyme A + H+ (EC 2.3.3.14)
BWI76_RS18860	-1.1
2 a [4Fe-4S] iron-sulfur cluster + a NifB protein→a NifB protein carrying two K-clusters
No genes
a NifB protein carrying two K-clusters + an oxidized ferredoxin [iron-sulfur] cluster + 2 S-adenosyl-L-methionine + a sulfurated [sulfur carrier]→a NifB protein carrying an L-cluster + S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + 3 H+ + a reduced ferredoxin [iron-sulfur] cluster + an unsulfurated [sulfur carrier]
No genes
a NifB protein carrying an L-cluster + a NifEN protein complex→a NifEN protein complex carrying an L-cluster + a NifB protein
BWI76_RS18835	-1.5
(2R)-homocitrate + a NifEN protein complex carrying an L-cluster + ATP + a NifQ protein with a [Mo-Fe-S] cluster→a NifEN protein complex carrying an M-cluster + ADP + phosphate + H2O + an apo NifQ protein
No genes
a NifEN protein complex carrying an M-cluster + a NifDK protein complex→a NifDK protein carrying an M-cluster + a NifEN protein complex
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information