MetaCyc Pathway: pyruvate fermentation to acetate IV in Bacteroides thetaiotaomicron VPI-5482

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Reactions and Genes BHIS with Trimethoprim 0.00625 mM
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Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate
(EC 2.3.1.54)
BT1055 +1.1
BT2955 +0.0
BT2956 -0.3
BT4737 -2.4
BT4738 -2.1
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A
(EC 2.3.1.8)
BT3692 N.D.
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP
(EC 2.7.2.1; 2.7.2.15)
BT0704 +0.7
BT3693 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information