MetaCyc Pathway: L-glutamate and L-glutamine biosynthesis in Bacteroides thetaiotaomicron VPI-5482

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Reactions and Genes Varel_Bryant_medium_Glucose with Econazole nitrate salt 0.025 mM
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Glutamate dehydrogenase (NAD(P)(+)) (in reverse):
2-oxoglutarate + ammonium + NAD(P)H + H+→L-glutamate + NAD(P)+ + H2O (EC 1.4.1.3)
No genes
Glutamate synthase (ferredoxin) (in reverse):
2-oxoglutarate + L-glutamine + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2 L-glutamate + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.4.7.1)
No genes
Glutamate synthase (NADH) (in reverse):
2-oxoglutarate + L-glutamine + NADH + H+→2 L-glutamate + NAD+ (EC 1.4.1.14)
BT0552 +0.4
BT4310 -1.7
Glutamate synthase (NADPH):
L-glutamine + H2O→L-glutamate + ammonia + H+ (EC 1.4.1.13; 1.4.1.14; 1.4.7.1; 2.6.1.85; 3.5.1.2; 3.5.1.38; 4.1.3.27; 4.3.2.10; 4.3.3.6; 6.3.4.2; 6.3.5.13; 6.3.5.2; 6.3.5.4; 6.3.5.5; 6.3.5.6; 6.3.5.7)
BT0531 -0.7
BT0532 -3.2
BT0551 -0.3
BT0552 +0.4
BT0553 +0.1
BT0556 +0.8
BT0557 +0.4
BT0583 -0.3
BT0590 N.D.
BT0767 -0.9
BT2419 +0.3
BT2571 +0.5
BT3364 N.D.
BT3555 +0.0
BT3641 +1.5
BT3808 N.D.
BT3866 -0.4
BT4265 +0.9
BT4310 -1.7
Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)
BT0543 +0.3
BT0785 +0.4
BT4339 -1.1
Glutamate dehydrogenase (NADP(+)) (in reverse):
2-oxoglutarate + ammonium + NADPH + H+→L-glutamate + NADP+ + H2O (EC 1.4.1.4)
BT1970 -2.4
BT1973 +1.0
Glutamate synthase (NADPH) (in reverse):
2-oxoglutarate + ammonia + NADPH + 2 H+→L-glutamate + NADP+ + H2O (EC 1.4.1.13; 1.4.1.14)
BT0552 +0.4
BT0553 +0.1
BT0583 -0.3
BT3364 N.D.
BT3555 +0.0
BT3641 +1.5
BT3808 N.D.
BT4310 -1.7

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information