MetaCyc Pathway: dipicolinate biosynthesis in Pantoea sp. MT58

Reactions and Genes	Survival; Treatment=UGA synthetic gw pH7.4 with 1 mM Glucose and 5 mM NaH2PO4; TreatmentDuration=24hrs; Outgrowth=LBkan50
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Aspartate kinase: L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4)
IAI47_00885	-1.7
IAI47_16215	-0.2
IAI47_17960	+0.1
Aspartate-semialdehyde dehydrogenase (in reverse): L-aspartyl-4-phosphate + NADPH + H⁺→L-aspartate 4-semialdehyde + NADP⁺ + phosphate (EC 1.2.1.11)
IAI47_01675	N.D.
IAI47_06240	-1.6
L-aspartate 4-semialdehyde + pyruvate→(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H⁺ + H₂O (EC 4.3.3.7)
IAI47_04285	+0.3
IAI47_05265	N.D.
IAI47_10125	+0.2
IAI47_15745	-0.3
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD⁺→dipicolinate + NADH + H⁺ + H₂O
No genes

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Pathway details at MetaCyc
Fitness data for 9 genes
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All MetaCyc pathways for Pantoea sp. MT58

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information