MetaCyc Pathway: polyisoprenoid biosynthesis (E. coli) in Klebsiella michiganensis M5al

Add experiment(s):


Reactions and Genes Fungal_growth_media_mCAFEs_v1_noCarbon with Supernatant; Trichoderma virens G41 grown in Fungal_growth_media_mCAFEs_v1, filtered and pH-adjusted 0.67x; and D-Glucose 37 mM
remove
Dimethylallyltranstransferase:
prenyl diphosphate + 3-methylbut-3-en-1-yl diphosphate→geranyl diphosphate + diphosphate (EC 2.5.1.1)
BWI76_RS06385 N.D.
Geranyltranstransferase:
geranyl diphosphate + 3-methylbut-3-en-1-yl diphosphate→(2E,6E)-farnesyl diphosphate + diphosphate (EC 2.5.1.10)
BWI76_RS06385 N.D.
(2E,6E)-farnesyl diphosphate + 5 3-methylbut-3-en-1-yl diphosphate→all-trans-octaprenyl diphosphate + 5 diphosphate (EC 2.5.1.90)
BWI76_RS25190 N.D.
Di-trans,poly-cis-decaprenylcistransferase:
(2E,6E)-farnesyl diphosphate + 8 3-methylbut-3-en-1-yl diphosphate→di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate (EC 2.5.1.31)
BWI76_RS05240 N.D.
Undecaprenyl-diphosphatase:
di-trans,octa-cis-undecaprenyl diphosphate + H2O→di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate (EC 3.6.1.27)
BWI76_RS09155 +0.2
BWI76_RS11950 +0.4
BWI76_RS19765 -1.0
BWI76_RS24480 +1.4

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information