MetaCyc Pathway: pyrimidine deoxyribonucleosides salvage in Bacteroides thetaiotaomicron VPI-5482

Add experiment(s):


Reactions and Genes BHIS with 5-Fluorouracil 0.1 mM
remove
Cytidine deaminase:
2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium (EC 3.5.4.5)
BT1539 -0.9
Deoxycytidine kinase:
2'-deoxycytidine + a nucleoside triphosphate→dCMP + a nucleoside diphosphate + H+ (EC 2.7.1.74)
No genes
Deoxynucleoside kinase:
2'-deoxyuridine + ATP→dUMP + ADP + H+ (EC 2.7.1.145; 2.7.1.21)
BT2275 +8.7
Thymidylate synthase:
dUMP + a 5,10-methylenetetrahydrofolate→dTMP + a 7,8-dihydrofolate (EC 2.1.1.45)
BT2047 N.D.
Deoxynucleoside kinase:
thymidine + ATP→dTMP + ADP + H+ (EC 2.7.1.145; 2.7.1.21)
BT2275 +8.7

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information