MetaCyc Pathway: nucleoside and nucleotide degradation (archaea) in Bacteroides thetaiotaomicron VPI-5482

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Reactions and Genes BHIS with 5-Fluorouracil 0.1 mM
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Purine-nucleoside phosphorylase:
adenosine + phosphate→α-D-ribose-1-phosphate + adenine
(EC 2.4.2.1)
BT1881 -1.1
BT4554 +3.7
cytidine + ATP→CMP + ADP + H+ (EC 2.7.1.213; 2.7.1.48)
BT0184 -1.1
BT2527 +0.4
UMP + phosphate→α-D-ribose 1,5-bisphosphate + uracil (EC 2.4.2.57)
No genes
AMP + phosphate→α-D-ribose 1,5-bisphosphate + adenine (EC 2.4.2.57)
No genes
Purine-nucleoside phosphorylase:
guanosine + phosphate→α-D-ribose-1-phosphate + guanine
(EC 2.4.2.1; 2.4.2.15)
BT1881 -1.1
BT4554 +3.7
Pyrimidine-nucleoside phosphorylase:
uridine + phosphate→α-D-ribose-1-phosphate + uracil
(EC 2.4.2.2; 2.4.2.3)
BT4554 +3.7
CMP + phosphate→α-D-ribose 1,5-bisphosphate + cytosine (EC 2.4.2.57)
No genes
α-D-ribose-1-phosphate + ADP→AMP + α-D-ribose 1,5-bisphosphate + H+ (EC 2.7.1.212)
No genes
α-D-ribose 1,5-bisphosphate→D-ribulose-1,5-bisphosphate (EC 5.3.1.29)
No genes
Ribulose-bisphosphate carboxylase (in reverse):
D-ribulose-1,5-bisphosphate + CO2 + H2O→2 3-phospho-D-glycerate + 2 H+
(EC 4.1.1.39)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information