MetaCyc Pathway: heme d1 biosynthesis in Pseudomonas fluorescens FW300-N1B4

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Reactions and Genes Nitrate reduction, replicate C t1
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siroheme + 2 H+→12,18-didecarboxysiroheme + 2 CO2 (EC 4.1.1.111)
Pf1N1B4_5768 +2.4
Pf1N1B4_5770 N.D.
Pf1N1B4_5771 N.D.
12,18-didecarboxysiroheme + 2 S-adenosyl-L-methionine + 2 H2O→pre-heme d1 + 2 5'-deoxyadenosine + 2 L-methionine + 2 propanoate + 2 H+
No genes
pre-heme d1 + an oxidized electron carrier→ferroheme d1 + a reduced two electron carrier
Pf1N1B4_5767 +2.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information