MetaCyc Pathway: reductive monocarboxylic acid cycle in Bacteroides thetaiotaomicron VPI-5482

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Reactions and Genes BHIS with Trimethoprim 0.00625 mM
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Pyruvate synthase (in reverse):
acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
BT1747 +1.7
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
BT1055 +0.2
BT2955 -0.1
BT2956 -0.3
BT4737 -1.1
BT4738 -1.8

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information