MetaCyc Pathway: NAD(P)/NADPH interconversion in Bacteroides thetaiotaomicron VPI-5482
| Reactions and Genes | BHIS with Trimethoprim 0.00625 mM |
|---|---|
| remove | |
| NAD(+) kinase: NAD+ + ATP→NADP+ + ADP + H+ (EC 2.7.1.23; 2.7.1.M29) | |
| BT3917 | N.D. |
| NADP+ + H2O→NAD+ + phosphate (EC 3.1.3.108) | |
| No genes | |
| NAD+[in] + 4 H+[out] + a ubiquinol→NADH[in] + 5 H+[in] + a ubiquinone (EC 7.1.1.2) | |
| BT1537 | -0.5 |
| BT2434 | -0.6 |
| BT4058 | +0.1 |
| BT4059 | +0.0 |
| BT4060 | +0.2 |
| BT4061 | +0.2 |
| BT4062 | +0.7 |
| BT4063 | -0.9 |
| BT4064 | +1.7 |
| BT4065 | +0.4 |
| BT4066 | +0.2 |
| BT4067 | -0.3 |
| NAD(P)(+) transhydrogenase (B-specific): NAD+ + NADPH→NADH + NADP+ (EC 1.6.1.1; 1.6.1.3) | |
| No genes | |
| NADPH + H2O→NADH + phosphate (EC 3.1.3.108) | |
| No genes | |
| NADH kinase: NADH + ATP→NADPH + ADP + H+ (EC 2.7.1.86; 2.7.1.M29) | |
| No genes | |
Links:
- Pathway details at MetaCyc
- Fitness data for 13 genes
- All MetaCyc pathways for Bacteroides thetaiotaomicron VPI-5482
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information