MetaCyc Pathway: glycine biosynthesis II in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes L-Leucine (C)
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a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine + CO2→glycine + a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine + H+ (EC 1.4.1.27; 1.4.4.2)
Pf6N2E2_5558 -0.1
a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine + NADH + H+→a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine + NAD+ (EC 1.4.1.27; 1.8.1.4)
Pf6N2E2_4251 +0.0
Pf6N2E2_478 -4.7
Pf6N2E2_5857 N.D.
a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine + ammonium + a 5,10-methylenetetrahydrofolate→a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine + a tetrahydrofolate (EC 1.4.1.27; 2.1.2.10)
Pf6N2E2_2778 -0.0
Pf6N2E2_2779 -0.1
Pf6N2E2_4485 +0.2
Pf6N2E2_4486 -0.5
Pf6N2E2_5556 +0.2
Pf6N2E2_5559 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information