MetaCyc Pathway: caffeine degradation III (bacteria, via demethylation) in Burkholderia phytofirmans PsJN

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Reactions and Genes 2-Deoxyadenosine 5-monophosphate 5 mM (C)
remove
caffeine + NAD(P)H + dioxygen + H+→theobromine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.178)
No genes
caffeine + NAD(P)H + dioxygen + H+→paraxanthine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.179)
No genes
theobromine + NAD(P)H + dioxygen + H+→7-methylxanthine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.179)
No genes
paraxanthine + NAD(P)H + dioxygen + H+→7-methylxanthine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.178)
No genes
7-methylxanthine + NAD(P)H + dioxygen + H+→xanthine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.128)
No genes
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
BPHYT_RS03865 +0.9
BPHYT_RS03870 +0.7
BPHYT_RS10825 N.D.
BPHYT_RS15080 +2.1
BPHYT_RS15085 +1.8
BPHYT_RS20910 +0.0
BPHYT_RS20915 N.D.
BPHYT_RS24595 +0.1
BPHYT_RS29710 +0.0
BPHYT_RS29715 +0.0
Xanthine oxidase:
xanthine + dioxygen + H2O→urate + hydrogen peroxide (EC 1.17.3.2)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information