MetaCyc Pathway: superpathway of purines degradation in plants in Burkholderia phytofirmans PsJN

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Reactions and Genes 2-Deoxyadenosine 5-monophosphate 5 mM (C)
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Adenosine-phosphate deaminase:
AMP + H+ + H2O→IMP + ammonium (EC 3.5.4.17; 3.5.4.6)
No genes
5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
BPHYT_RS01605 -0.6
BPHYT_RS03140 +0.0
BPHYT_RS09100 +0.5
BPHYT_RS26570 +1.1
Guanosine deaminase:
guanosine + H+ + H2O→xanthosine + ammonium (EC 3.5.4.15)
No genes
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
BPHYT_RS10250 -0.2
BPHYT_RS12020 N.D.
BPHYT_RS13715 -0.3
BPHYT_RS24710 N.D.
BPHYT_RS27545 -0.2
BPHYT_RS31260 -0.3
5'-nucleotidase:
IMP + H2O→inosine + phosphate (EC 3.1.3.5; 3.1.3.99)
BPHYT_RS01605 -0.6
BPHYT_RS03140 +0.0
BPHYT_RS09100 +0.5
BPHYT_RS26570 +1.1
Purine nucleosidase:
guanosine + H2O→guanine + D-ribofuranose (EC 3.2.2.1)
BPHYT_RS20700 -0.7
BPHYT_RS21970 -0.3
BPHYT_RS24460 +0.2
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
BPHYT_RS11520 -0.2
BPHYT_RS15100 +0.2
Inosine nucleosidase:
inosine + H2O→hypoxanthine + D-ribofuranose (EC 3.2.2.2)
BPHYT_RS20700 -0.7
BPHYT_RS21970 -0.3
BPHYT_RS24460 +0.2
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
BPHYT_RS01605 -0.6
BPHYT_RS03140 +0.0
BPHYT_RS09100 +0.5
BPHYT_RS26570 +1.1
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
BPHYT_RS03865 +0.9
BPHYT_RS03870 +0.7
BPHYT_RS10825 N.D.
BPHYT_RS15080 +2.1
BPHYT_RS15085 +1.8
BPHYT_RS20910 +0.0
BPHYT_RS20915 N.D.
BPHYT_RS24595 +0.1
BPHYT_RS29710 +0.0
BPHYT_RS29715 +0.0
Purine nucleosidase:
xanthosine + H2O→xanthine + D-ribofuranose (EC 3.2.2.1)
BPHYT_RS20700 -0.7
BPHYT_RS21970 -0.3
BPHYT_RS24460 +0.2
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
BPHYT_RS03865 +0.9
BPHYT_RS03870 +0.7
BPHYT_RS10825 N.D.
BPHYT_RS15080 +2.1
BPHYT_RS15085 +1.8
BPHYT_RS20910 +0.0
BPHYT_RS20915 N.D.
BPHYT_RS24595 +0.1
BPHYT_RS29710 +0.0
BPHYT_RS29715 +0.0
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
BPHYT_RS11550 N.D.
BPHYT_RS11555 -0.2
BPHYT_RS26115 +0.7
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
BPHYT_RS11530 -2.2
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes
Allantoinase:
(S)-(+)-allantoin + H2O→allantoate + H+ (EC 3.5.2.5)
No genes
Allantoicase:
allantoate + H2O→(S)-ureidoglycolate + urea (EC 3.5.3.4)
BPHYT_RS11545 +1.6
BPHYT_RS16820 -0.0
Ureidoglycolate lyase:
(S)-ureidoglycolate→glyoxylate + urea (EC 4.3.2.3)
BPHYT_RS11540 -0.3
BPHYT_RS16815 +1.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information