MetaCyc Pathway: superpathway of L-cysteine biosynthesis (mammalian) in Xanthomonas campestris pv. campestris strain 8004

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Reactions and Genes D-Glucose 16.67 mM (C)
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Methionine adenosyltransferase:
L-methionine + ATP + H2O→S-adenosyl-L-methionine + diphosphate + phosphate (EC 2.5.1.6)
Xcc-8004.4305.1 N.D.
S-adenosyl-L-homocysteine + a methylated methyl acceptor + H+→S-adenosyl-L-methionine + a demethylated methyl acceptor
No genes
S-adenosyl-L-homocysteine + H2O→L-homocysteine + adenosine (EC 3.13.2.1)
Xcc-8004.2933.1 -0.5
Xcc-8004.4317.1 N.D.
Cystathionine beta-synthase:
L-homocysteine + L-serine→L-cystathionine + H2O (EC 4.2.1.22)
Xcc-8004.4518.1 +1.3
Cystathionine gamma-lyase:
L-cystathionine + H2O→L-cysteine + 2-oxobutanoate + ammonium (EC 4.4.1.1)
Xcc-8004.4517.1 +0.9

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information