MetaCyc Pathway: glutathione-mediated detoxification II in Phaeobacter inhibens DSM 17395

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Reactions and Genes Glycine (C)
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Glutathione transferase:
RX + glutathione→a glutathione-S-conjugate + HX (EC 2.5.1.18)
PGA1_c12050 -0.3
PGA1_c13330 -0.1
PGA1_c23760 -3.5
PGA1_c24280 -0.1
PGA1_c26690 -0.2
PGA1_c32680 -0.0
PGA1_c33430 +0.3
PGA1_c36120 N.D.
PGA1_c36190 +0.0
PGA1_262p01130 -0.3
PGA1_c00380 +0.0
PGA1_c04470 +0.0
PGA1_c07460 +0.1
PGA1_c00840 +0.0
a glutathione-S-conjugate[in] + ATP[in] + H2O[in]→a glutathione-S-conjugate[out] + ADP[in] + H+[in] + phosphate[in] (EC 7.6.2.3)
No genes
a glutathione-S-conjugate + H2O→a [γ-glutamyl-L-cysteine]-S-conjugate + glycine (EC 3.4.17.25)
No genes
a glutathione-S-conjugate + H2O→an (L-cysteinylglycine)-S-conjugate + L-glutamate (EC 3.4.19.13)
No genes
a [γ-glutamyl-L-cysteine]-S-conjugate + H2O→an L-cysteine-S-conjugate + L-glutamate (EC 3.4.13.M2)
No genes
an (L-cysteinylglycine)-S-conjugate + H2O→an L-cysteine-S-conjugate + glycine (EC 3.4.13.23)
No genes
an L-cysteine-S-conjugate + malonyl-CoA→an N-malonyl-L-cysteine-S-conjugate + coenzyme A + H+
No genes
Cysteine-S-conjugate beta-lyase:
an L-cysteine-S-conjugate + H2O→a thiol + ammonium + pyruvate (EC 4.4.1.13)
No genes
Thiol S-methyltransferase:
a thiol + S-adenosyl-L-methionine→a methyl thioether + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.9)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information