MetaCyc Pathway: L-tryptophan degradation II (via pyruvate) in Bacteroides thetaiotaomicron VPI-5482
| Reactions and Genes | Varel_Bryant medium with Zinc Pyrithione 0.05 mM |
|---|---|
| remove | |
| Tryptophanase: L-tryptophan→2-aminoprop-2-enoate + indole (EC 4.1.99.1) | |
| BT1492 | -0.2 |
| Tryptophanase: 2-aminoprop-2-enoate→2-iminopropanoate (spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2) | |
| BT1492 | -0.2 |
| BT4678 | +1.3 |
| 2-iminopropanoate + H2O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2) | |
| BT1336 | -1.2 |
| BT1492 | -0.2 |
| BT4678 | +1.3 |
Links:
- Pathway details at MetaCyc
- Fitness data for 3 genes
- All MetaCyc pathways for Bacteroides thetaiotaomicron VPI-5482
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information