MetaCyc Pathway: L-glutamate and L-glutamine biosynthesis in Pseudomonas syringae pv. syringae B728a

Add experiment(s):


Reactions and Genes L-Malic (C)
remove
Glutamate dehydrogenase (NAD(P)(+)) (in reverse):
2-oxoglutarate + ammonium + NAD(P)H + H+→L-glutamate + NAD(P)+ + H2O (EC 1.4.1.3)
No genes
Glutamate synthase (ferredoxin) (in reverse):
2-oxoglutarate + L-glutamine + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2 L-glutamate + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.4.7.1)
No genes
Glutamate synthase (NADH) (in reverse):
2-oxoglutarate + L-glutamine + NADH + H+→2 L-glutamate + NAD+ (EC 1.4.1.14)
Psyr_0412 -3.8
Glutamate synthase (NADPH):
L-glutamine + H2O→L-glutamate + ammonia + H+ (EC 1.4.1.13; 1.4.1.14; 1.4.7.1; 2.6.1.85; 3.5.1.2; 3.5.1.38; 4.1.3.27; 4.3.2.10; 4.3.3.6; 6.3.4.2; 6.3.5.13; 6.3.5.2; 6.3.5.4; 6.3.5.5; 6.3.5.6; 6.3.5.7)
Psyr_0262 +0.3
Psyr_0411 -4.1
Psyr_0412 -3.8
Psyr_0418 +0.2
Psyr_0616 +0.5
Psyr_1014 -0.2
Psyr_1262 N.D.
Psyr_1280 -0.4
Psyr_1361 N.D.
Psyr_2035 +0.2
Psyr_2058 N.D.
Psyr_2072 -2.0
Psyr_2080 -0.4
Psyr_2145 N.D.
Psyr_2275 -0.0
Psyr_2276 -0.0
Psyr_2292 +1.5
Psyr_2426 N.D.
Psyr_2765 -0.1
Psyr_2911 -0.1
Psyr_3058 -0.4
Psyr_3240 +0.4
Psyr_3260 +0.2
Psyr_3668 N.D.
Psyr_3747 -0.3
Psyr_3938 -0.8
Psyr_4015 -0.4
Psyr_4055 -1.4
Psyr_4164 N.D.
Psyr_4165 N.D.
Psyr_4166 N.D.
Psyr_4191 N.D.
Psyr_4192 N.D.
Psyr_4315 +0.0
Psyr_4375 -0.2
Psyr_4465 +0.0
Psyr_4581 -5.3
Psyr_4609 -4.2
Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)
Psyr_2273 -0.8
Psyr_3492 +0.0
Psyr_4817 N.D.
Psyr_4867 -0.8
Psyr_4868 -0.0
Glutamate dehydrogenase (NADP(+)) (in reverse):
2-oxoglutarate + ammonium + NADPH + H+→L-glutamate + NADP+ + H2O (EC 1.4.1.4)
Psyr_0412 -3.8
Glutamate synthase (NADPH) (in reverse):
2-oxoglutarate + ammonia + NADPH + 2 H+→L-glutamate + NADP+ + H2O (EC 1.4.1.13; 1.4.1.14)
Psyr_0262 +0.3
Psyr_0411 -4.1
Psyr_0412 -3.8
Psyr_0418 +0.2
Psyr_0616 +0.5
Psyr_1014 -0.2
Psyr_1280 -0.4
Psyr_2035 +0.2
Psyr_2058 N.D.
Psyr_2072 -2.0
Psyr_2145 N.D.
Psyr_2275 -0.0
Psyr_2276 -0.0
Psyr_2426 N.D.
Psyr_2765 -0.1
Psyr_2911 -0.1
Psyr_3260 +0.2
Psyr_3668 N.D.
Psyr_4015 -0.4
Psyr_4055 -1.4
Psyr_4375 -0.2
Psyr_4465 +0.0

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information