MetaCyc Pathway: mannitol biosynthesis in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Nickel (II) chloride 0.5 mM
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Mannose-6-phosphate isomerase (in reverse):
β-D-fructofuranose 6-phosphate→D-mannopyranose 6-phosphate (EC 5.3.1.8)
Pf6N2E2_2741 -0.1
Pf6N2E2_3574 -1.5
Pf6N2E2_5377 -0.1
Pf6N2E2_5763 -0.2
Mannose-6-phosphate 6-reductase (in reverse):
D-mannopyranose 6-phosphate + NADPH + H+→D-mannitol 1-phosphate + NADP+ (EC 1.1.1.224)
No genes
Mannitol-1-phosphatase:
D-mannitol 1-phosphate + H2O→D-mannitol + phosphate (EC 3.1.3.22)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information