MetaCyc Pathway: queuosine biosynthesis III (queuosine salvage) in Klebsiella michiganensis M5al

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Reactions and Genes Sisomicin 0.008 mg/ml
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queuosine + H2O→queuine + D-ribose (EC 3.2.2.M3)
No genes
queuine + S-adenosyl-L-methionine→preQ1 + 5'-deoxyadenosine + 2-hydroxycyclopenta-2,4-dien-1-one + L-methionine + H+ (EC 4.3.99.M4)
No genes
tRNA-guanine transglycosylase:
preQ1 + a guanine34 in tRNA→a 7-aminomethyl-7-deazaguanosine34 in tRNA + guanine (EC 2.4.2.29)
BWI76_RS06300 N.D.
a 7-aminomethyl-7-deazaguanosine34 in tRNA + S-adenosyl-L-methionine→an epoxyqueuosine34 in tRNA + adenine + L-methionine + H+ (EC 2.4.99.17)
BWI76_RS06295 -0.6
an epoxyqueuosine34 in tRNA + a reduced two electron carrier→a queuosine34 in tRNA + an oxidized electron carrier + H2O (EC 1.17.99.6)
BWI76_RS02505 -1.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information