MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas syringae pv. syringae B728a

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Reactions and Genes Fumaric (C)
remove
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Psyr_0117 -0.1
Psyr_0230 +0.3
Psyr_1841 +0.3
Psyr_1973 +0.5
Psyr_2000 +0.0
Psyr_2910 +0.1
Psyr_3087 -0.0
Psyr_3615 -2.5
Psyr_4132 -3.4
Psyr_4325 -0.1
Psyr_4898 -2.6
Psyr_5056 +0.0
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2
(EC 1.13.11.27)
Psyr_2130 -0.1
Psyr_3330 -0.1
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+
(EC 1.13.11.5)
Psyr_3326 +0.0
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate
(EC 5.2.1.2)
No genes
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+
(EC 3.7.1.2)
Psyr_3325 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information