MetaCyc Pathway: glycine betaine degradation I in Pseudomonas syringae pv. syringae B728a

Add experiment(s):


Reactions and Genes Citric Acid (C)
remove
Betaine--homocysteine S-methyltransferase:
glycine betaine + L-homocysteine→N,N-dimethylglycine + L-methionine (EC 2.1.1.5)
No genes
Dimethylglycine oxidase:
N,N-dimethylglycine + dioxygen + a tetrahydrofolate→sarcosine + hydrogen peroxide + a 5,10-methylenetetrahydrofolate (EC 1.5.3.10)
No genes
sarcosine + dioxygen + a tetrahydrofolate→glycine + hydrogen peroxide + a 5,10-methylenetetrahydrofolate (EC 1.5.3.24)
Psyr_2223 +0.4
Psyr_4713 -0.1
Psyr_4714 +0.2
Sarcosine oxidase:
sarcosine + dioxygen + H2O→glycine + formaldehyde + hydrogen peroxide (EC 1.5.3.1)
Psyr_2221 +0.1
Psyr_2222 -0.1
Psyr_2223 +0.4
Psyr_2224 -0.2
Psyr_2330 +0.9
Psyr_3158 -0.0
Psyr_4713 -0.1
Psyr_4714 +0.2
Psyr_4715 +0.0
Psyr_4716 -1.4
Glycine hydroxymethyltransferase (in reverse):
glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate (EC 2.1.2.1)
Psyr_4270 -3.6
Psyr_4712 +0.0
L-serine ammonia-lyase:
L-serine→2-aminoprop-2-enoate + H2O (EC 4.3.1.17)
Psyr_3522 -0.6
Tryptophanase:
2-aminoprop-2-enoate→2-iminopropanoate (spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
Psyr_0359 -1.1
Psyr_2509 -0.2
Psyr_3522 -0.6
2-iminopropanoate + H2O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
Psyr_0208 -0.0
Psyr_0359 -1.1
Psyr_2509 -0.2
Psyr_3522 -0.6

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information