MetaCyc Pathway: aromatic biogenic amine degradation (bacteria) in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Chromium(III) Chloride Hexahydrate 0.000390625 M
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Octopamine dehydratase:
octopamine→(4-hydroxyphenyl)acetaldehyde + ammonium (EC 4.2.1.87)
No genes
tyramine + an oxidized electron carrier + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + a reduced two electron carrier
No genes
Monoamine oxidase:
tyramine + dioxygen + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
Pf6N2E2_4632 -1.7
Monoamine oxidase:
dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
Pf6N2E2_4632 -1.7
Synephrine dehydratase:
(R)-synephrine→(4-hydroxyphenyl)acetaldehyde + methylamine (EC 4.2.1.88)
No genes
4-hydroxyphenylacetaldehyde dehydrogenase:
(4-hydroxyphenyl)acetaldehyde + NAD+ + H2O→(4-hydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.53)
Pf6N2E2_1329 +0.5
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.3)
Pf6N2E2_1381 -0.3
Pf6N2E2_1764 -0.1
Pf6N2E2_1854 +0.1
Pf6N2E2_1874 N.D.
Pf6N2E2_1878 -0.4
Pf6N2E2_1906 +0.2
Pf6N2E2_1919 -0.0
Pf6N2E2_225 -0.4
Pf6N2E2_3298 +0.2
Pf6N2E2_351 -0.1
Pf6N2E2_3582 -0.1
Pf6N2E2_4383 -0.0
Pf6N2E2_4964 +0.0
Pf6N2E2_4979 +0.1
Pf6N2E2_5476 -1.3
Pf6N2E2_935 +0.1
(4-hydroxyphenyl)acetate + FADH2 + dioxygen→(3,4-dihydroxyphenyl)acetate + FAD + H+ + H2O (EC 1.14.14.9)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information