MetaCyc Pathway: L-tryptophan degradation X (mammalian, via tryptamine) in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Chromium(III) Chloride Hexahydrate 0.000390625 M
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L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
No genes
Monoamine oxidase:
tryptamine + dioxygen + H2O→(indol-3-yl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
Pf6N2E2_4632 -1.7
Indole-3-acetaldehyde reductase (NADPH) (in reverse):
(indol-3-yl)acetaldehyde + NADPH + H+→(indol-3-yl)ethanol + NADP+ (EC 1.1.1.191; 1.1.1.2)
No genes
Aldehyde dehydrogenase (NAD(+)):
(indol-3-yl)acetaldehyde + NAD+ + H2O→(indol-3-yl)acetate + NADH + 2 H+ (EC 1.2.1.3)
Pf6N2E2_1381 -0.3
Pf6N2E2_1764 -0.1
Pf6N2E2_1854 +0.1
Pf6N2E2_1874 N.D.
Pf6N2E2_1878 -0.4
Pf6N2E2_1906 +0.2
Pf6N2E2_1919 -0.0
Pf6N2E2_225 -0.4
Pf6N2E2_3298 +0.2
Pf6N2E2_351 -0.1
Pf6N2E2_3582 -0.1
Pf6N2E2_4383 -0.0
Pf6N2E2_4964 +0.0
Pf6N2E2_4979 +0.1
Pf6N2E2_5476 -1.3
Pf6N2E2_935 +0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information