MetaCyc Pathway: desferrioxamine E biosynthesis in Mycobacterium tuberculosis H37Rv

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Reactions and Genes pH 4.5
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Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
Rv2531c +1.2
cadaverine + a reduced two electron carrier + dioxygen→N-hydroxycadaverine + an oxidized electron carrier + H+ + H2O
No genes
N-hydroxycadaverine + succinyl-CoA→N-hydroxy-N-succinylcadaverine + coenzyme A
No genes
3 N-hydroxy-N-succinylcadaverine + ATP→desferrioxamine G1 + AMP + diphosphate + H+ + H2O
No genes
desferrioxamine G1 + ATP→desferrioxamine E + AMP + diphosphate + H+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information