MetaCyc Pathway: γ-linolenate biosynthesis II (animals) in Mycobacterium tuberculosis H37Rv

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Reactions and Genes pH 4.5
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Long-chain-fatty-acid--CoA ligase:
linoleate + ATP + coenzyme A→linoleoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
Rv0166 -0.0
Rv0214 +0.2
Rv0270 +2.2
Rv1013 -2.0
Rv1058 +0.4
Rv1427c -0.7
Rv2187 +1.1
Rv2505c -0.2
Rv3506 -0.3
Rv3513c -1.5
Rv3515c -0.1
Rv3561 -0.3
Linoleoyl-CoA desaturase:
linoleoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→γ-linolenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.3)
Rv3229c +0.7

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information