MetaCyc Pathway: guanosine deoxyribonucleotides de novo biosynthesis II in Klebsiella michiganensis M5al

Add experiment(s):


Reactions and Genes Cobalt chloride 0.5 mM
remove
Ribonucleoside-diphosphate reductase (in reverse):
GDP + a reduced thioredoxin→dGDP + an oxidized thioredoxin + H2O
(EC 1.17.4.1)
BWI76_RS19940 N.D.
BWI76_RS19945 N.D.
BWI76_RS22050 -1.9
BWI76_RS22055 -1.7
BWI76_RS22060 -0.8
Ribonucleoside-diphosphate reductase (in reverse):
GDP + a reduced NrdH glutaredoxin-like protein→dGDP + an oxidized NrdH glutaredoxin-like protein + H2O
(EC 1.17.4.1)
BWI76_RS19940 N.D.
BWI76_RS19945 N.D.
BWI76_RS22055 -1.7
BWI76_RS22060 -0.8
Nucleoside-diphosphate kinase:
dGDP + ATP→dGTP + ADP
(EC 2.7.4.6)
BWI76_RS06840 N.D.
BWI76_RS21100 +0.5
GTP + formate + H+→dGTP + CO2 + H2O (EC 1.1.98.6)
BWI76_RS02935 +0.0

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information