MetaCyc Pathway: seleno-amino acid biosynthesis (plants) in Klebsiella michiganensis M5al

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Reactions and Genes Cobalt chloride 0.5 mM
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Serine O-acetyltransferase:
L-serine + acetyl-CoA→O-acetyl-L-serine + coenzyme A (EC 2.3.1.30)
BWI76_RS05560 N.D.
BWI76_RS27205 N.D.
Cysteine synthase:
O-acetyl-L-serine + hydrogen selenide→L-selenocysteine + acetate + H+ (EC 2.5.1.47)
BWI76_RS06575 +1.3
BWI76_RS20640 -0.7
BWI76_RS20685 N.D.
L-selenocysteine + O-phospho-L-homoserine→L-selenocystathionine + phosphate
No genes
Cysteine-S-conjugate beta-lyase:
L-selenocystathionine + H2O→seleno-L-homocysteine + ammonium + pyruvate (EC 4.4.1.13)
No genes
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase:
seleno-L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate→L-selenomethionine + tetrahydropteroyl tri-L-glutamate (EC 2.1.1.14)
BWI76_RS01280 +0.1
BWI76_RS15390 -0.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information