MetaCyc Pathway: pseudouridine degradation in Klebsiella michiganensis M5al

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Reactions and Genes Cobalt chloride 0.5 mM
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Pseudouridine kinase:
pseudouridine + ATP→pseudouridine 5'-phosphate + ADP + H+
(EC 2.7.1.83)
BWI76_RS19720 -0.2
Pseudouridylate synthase (in reverse):
pseudouridine 5'-phosphate + H2O→uracil + D-ribofuranose 5-phosphate
(EC 4.2.1.70)
BWI76_RS01755 -0.0
BWI76_RS04565 -0.2
BWI76_RS11050 -1.1
BWI76_RS11325 N.D.
BWI76_RS11880 +2.0
BWI76_RS17615 +0.6
BWI76_RS19715 +0.1
BWI76_RS19810 N.D.
BWI76_RS20380 -3.2
BWI76_RS21450 -1.5
BWI76_RS22850 -0.5
BWI76_RS25080 +4.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information