MetaCyc Pathway: glycolysis II (from fructose 6-phosphate) in Klebsiella michiganensis M5al

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Reactions and Genes Nickel (II) chloride 1.5 mM
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Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
BWI76_RS22790 N.D.
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
BWI76_RS04200 +0.3
BWI76_RS08605 -4.5
BWI76_RS13025 +0.4
BWI76_RS27230 -0.1
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
BWI76_RS00530 +0.0
BWI76_RS00735 N.D.
BWI76_RS17175 N.D.
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
BWI76_RS00545 +0.1
BWI76_RS14880 -0.3
BWI76_RS19370 -2.0
BWI76_RS23975 N.D.
BWI76_RS27560 +0.3
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
BWI76_RS02815 -0.6
BWI76_RS06160 -0.1
BWI76_RS08660 +0.2
BWI76_RS27445 +0.0
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
BWI76_RS11505 N.D.
BWI76_RS12975 -0.2
BWI76_RS13215 -0.7
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
BWI76_RS23980 N.D.
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
BWI76_RS08605 -4.5
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
BWI76_RS03100 +0.2
BWI76_RS27465 N.D.
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
BWI76_RS16960 N.D.
BWI76_RS18115 +0.1
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
BWI76_RS17065 +0.7

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information